Abstract Cancer remains a significant health issue, resulting in around 10 million deaths per year, particularly in developing nations.Demographic changes, socio-economic variables, and lifestyle choices are responsible for 7N@BP the rise in cancer cases.Despite the potential to mitigate the adverse effects of cancer by early detection and the impl
Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset
Abstract Animal studies have demonstrated Places Art the ability of pancreatic acinar cells to transform into pancreatic ductal adenocarcinoma (PDAC).However, the tumorigenic potential of human pancreatic acinar cells remains under debate.To address this gap in knowledge, we expand sorted human acinar cells as 3D organoids and genetically modify th
Small molecule suppressors of Drosophila kinesin deficiency rescue motor axon development in a zebrafish model of spinal muscular atrophy.
Gift Card Proximal spinal muscular atrophy (SMA) is the most common inherited motor neuropathy and the leading hereditary cause of infant mortality.Currently there is no effective treatment for the disease, reflecting a need for pharmacologic interventions that restore performance of dysfunctional motor neurons or suppress the consequences of their
Enhanced energy extraction in small-scale wind turbines through slot-based passive blowing
The increasing demand for sustainable energy has spurred research and development of wind turbines.In this study, a passive flow-control technique using a non-uniform curved slot is proposed.The slot is engraved on the mid-chord region FLORAVISION of the National Renewable Energy Laboratory (NREL) Phase VI wind turbine blade, between the quarter-sp